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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPSB2 All Species: 4.24
Human Site: S226 Identified Species: 11.67
UniProt: Q99619 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99619 NP_116030.1 263 28630 S226 E R R A E P H S L L H L S R L
Chimpanzee Pan troglodytes XP_525174 478 52950 P441 G L D P E P L P L M D L C R R
Rhesus Macaque Macaca mulatta XP_001113018 273 30174 P236 G L D P E P L P L M D L C R R
Dog Lupus familis XP_534903 263 28544 S226 G R R A E P H S L L H L S R L
Cat Felis silvestris
Mouse Mus musculus O88838 264 28919 Q226 E R R V E E P Q S L L H L S R
Rat Rattus norvegicus Q5M877 264 28778 Q226 E R R A E E P Q S L L H L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505755 273 31164 P236 G L D P E P L P L M D L C R R
Chicken Gallus gallus XP_417599 273 31045 P236 G L D P E P L P L M D L C R R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780123 272 30725 P235 G L E P S P L P L Q D L C R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.1 52 95.4 N.A. 90.5 91.2 N.A. 50.5 51.2 N.A. N.A. N.A. N.A. N.A. N.A. 47.4
Protein Similarity: 100 38.7 64 96.1 N.A. 92.8 93.9 N.A. 62.6 61.5 N.A. N.A. N.A. N.A. N.A. N.A. 60.2
P-Site Identity: 100 33.3 33.3 93.3 N.A. 33.3 40 N.A. 33.3 33.3 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 40 40 93.3 N.A. 33.3 40 N.A. 40 40 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % C
% Asp: 0 0 45 0 0 0 0 0 0 0 56 0 0 0 0 % D
% Glu: 34 0 12 0 89 23 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 23 0 0 0 23 23 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 56 0 0 0 0 56 0 78 45 23 78 23 0 23 % L
% Met: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 56 0 78 23 56 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 23 0 12 0 0 0 0 0 % Q
% Arg: 0 45 45 0 0 0 0 0 0 0 0 0 0 78 78 % R
% Ser: 0 0 0 0 12 0 0 23 23 0 0 0 23 23 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _